Takeda Pharmaceuticals (Takeda) fired several employees who refused to get the COVID-19 vaccine based on their religious beliefs. The company scored a 100 out of 100 on the 2023-2024 Corporate Equality Index (CEI) from the Human Rights Campaign (HRC), a political stakeholder group. By complying with the HRC’s controversial demands, the company increases the risk of dividing employees, alienating customers and harming shareholders. The company provides a benefits package for employees which covers transgender medical procedures for covered employees and dependents, including children. It also uses sex and gender ideology criteria in employee recruitment, vendor selection, marketing, and philanthropic support. Takeda forces employees to undergo multiple ideological trainings and uses its reputation, corporate funds, and political influence to support controversial sex and gender ideologies, organizations, and legislation. Takeda opposed various state and local legislation intended to protect parental rights, girls’ sports, bathroom facilities, and gendered spaces. The company signed the Health Sector Climate Pledge, committing itself to achieve net zero emissions by 2050. Takeda is a Bronze sponsor of the HRC. For these reasons, Takeda receives a High Risk rating.